SCHEMBL1492629

SCHEMBL1492629

Cc1[c]cc(C(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
PTGS1 P23219 2/20 0.37
TRPA1 O75762 1/20 0.37
CACNA1C Q13936 1/20 0.37
TYR P14679 2/20 0.34
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 2/20 0.32
NOTUM Q6P988 1/20 0.31
IDO1 P14902 2/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.31
HIF1A Q16665 1/20 0.31
PTGS2 P35354 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596731 0.78
SCHEMBL1188027 0.75 TYR (0.34) LMNAPTGS1TRPA1CACNA1CTYR
SCHEMBL191957 0.73 TYR (0.38) LMNATYRALDH1A1MAPK1HTT
SCHEMBL3602717 0.73 TYR (0.40) LMNAPTGS1TRPA1CACNA1CTYR
SCHEMBL17262605 0.73 TYR (0.33) LMNAPTGS1TRPA1CACNA1CTYR
SCHEMBL2585466 0.73 TYR (0.33) LMNAPTGS1TRPA1CACNA1CTYR
SCHEMBL2586636 0.70 IDO1 (0.32) LMNATYRIDO1
SCHEMBL162301 0.70 ALDH1A1 (0.37) LMNATYRALDH1A1MAPK1IDO1
SCHEMBL8782148 0.69 IDO1 (0.31) TYRIDO1
SCHEMBL104124 0.67 TYR (0.58) LMNAPTGS1TRPA1CACNA1CTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200399203-A1 PRODRUGS OF FENCAMFAMINE PRAXIS BIORESEARCH, INC. 2020-12-24 US claimed
CN-107082789-B Method for preparing organic phosphate compound by efficiently esterifying P (O) -OH-containing compound and phenol 湖南理工学院 2020-08-28 CN claimed
US-10662146-B2 Prodrugs of fencamfamine Praxis Bioresearch, LLC (US) 2020-05-26 US claimed
US-20190023650-A1 PRODRUGS OF FENCAMFAMINE Praxis Bioresearch, LLC 2019-01-24 US claimed
EP-3349853-A1 PRODRUGS OF FENCAMFAMINE Praxis Bioresearch, LLC (US) 2018-07-25 EP claimed
WO-2017048720-A1 PRODRUGS OF FENCAMFAMINE PRAXIS BIOSCIENCES, LLC (US) 2017-03-23 WO claimed
US-20110118234-A1 Urea Compounds as Gamma Secretase Modulators AMGEN INC. 2011-05-19 US claimed
EP-2300427-A1 UREA COMPOUNDS AS GAMMA SECRETASE MODULATORS AMGEN INC. (US) 2011-03-30 EP claimed
WO-2009137404-A1 UREA COMPOUNDS AS GAMMA SECRETASE MODULATORS AMGEN INC. (US) 2009-11-12 WO claimed
US-6008306-A COMPOSITION OF STRAINED CYCLOOLEFIN AND A DIVALENT CATIONIC RUTHENIUM OR OSMIUM BOUND TO 1-3 TERTIARY PHOSPHINE LIGANDS, THE PHOSPHINE GROUPS CONTAIN PHENYL SUBSTITUTED BY ALKYL, ALKOXY OR HALOALKYL GROUPS; IMPROVED CATALYTIC ACTIVITY CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-12-28 US claimed
EP-0513580-B1 Alpha-phenyl-acrylic acid derivatives, process for their preparation and their use as parasiticides and fungicides BASF AG (DE) 1996-10-23 EP claimed
US-5416068-A Alpha-phenylacrylic acid derivatives, their preparation and their use for controlling pests and harmful fungi BASF AKTIENGESELLSCHAFT (DE) 1995-05-16 US claimed
US-3959332-A N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES SANDOZ LTD. (CH) 1976-05-25 US claimed
JP-10045784-A None JP disclosed
EP-4452848-B1 PRECIPITATED SILICA AND METHODS THEREOF EVONIK OPERATIONS GMBH (DE) 2025-10-08 EP disclosed
US-20250100959-A1 METHOD FOR STORING REDUCED COENZYME Q10 KANEKA CORPORATION (JP) 2025-03-27 US disclosed
EP-0360085-A2 Offset printing and offset dyestuffs BAYER AG (DE) 1990-03-28 EP disclosed
US-4420437-A Preparation of a 2-aralkyl-5,5-dialkyl-1,3,2-dioxaphosphorinan-2-one from 2-aralkoxy-5,5-dialkyl-1,3,2-dioxaphosphorinane WITCO CHEMICAL CORPORATION (US) 1983-12-13 US disclosed
US-4107138-A Phosphonous and thiophosphonous acid ethers as stabilizers for organic materials SANDOZ LTD. (CH) 1978-08-15 US disclosed
US-3987097-A INCREASING AFFINITY FOR ANIONIC DYES SANDOZ LTD. (CH) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118234-A1 Urea Compounds as Gamma Secretase Modulators BACE1, BACE2, PSEN1 LMNA 1262/4885PTGS1 1182/4885TRPA1 4420/4885
US-20190023650-A1 PRODRUGS OF FENCAMFAMINE FOLR2, FOLR1, CYP4F2 LMNA 1726/4885PTGS1 326/4885TRPA1 2822/4885
US-10662146-B2 Prodrugs of fencamfamine FEN1, PNMT, SLC19A1 LMNA 3919/4885PTGS1 2356/4885TRPA1 3760/4885
US-20200399203-A1 PRODRUGS OF FENCAMFAMINE FOLR2, FOLR1, CYP4F2 LMNA 1726/4885PTGS1 326/4885TRPA1 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.