Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127673 | 0.83 | RAC1 (0.40) | ADORA1MEN1KMT2ADHODHALDH1A1 | |
| SCHEMBL14926972 | 0.80 | ESR1 (0.39) | ADORA2AMEN1KMT2AL3MBTL1NUDT1 | |
| SCHEMBL14926977 | 0.80 | SQOR (0.40) | ADORA1ADORA2AMEN1KMT2APIM1 | |
| SCHEMBL14926975 | 0.78 | ADORA3 (0.43) | ADORA1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL128848 | 0.76 | RAC1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14926981 | 0.76 | ADORA3 (0.49) | ADORA1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL128040 | 0.75 | RAC1 (0.44) | MEN1KMT2ADHODHALDH1A1MAPT | |
| SCHEMBL12070505 | 0.74 | RAD52 (0.53) | ADORA1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL14926974 | 0.74 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL14926976 | 0.73 | TLR9 (0.52) | MEN1KMT2APIM1SMARCA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | ACHE 2854/4885ADORA1 357/4885ADORA2A 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.