Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAC1 | P63000 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.37 |
| ▸ | TUBB | P07437 | 4/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985556 | 0.88 | RAC1 (0.48) | RAC1ADORA3TUBB4ATUBBTUBA3C | |
| SCHEMBL195376 | 0.77 | RAC1 (0.69) | RAC1ADORA3ALDH1A1GAAALOX15 | |
| SCHEMBL14927114 | 0.77 | HTT (0.39) | ALDH1A1HSD17B10PDGFRBKDM4EMAPT | |
| SCHEMBL14927115 | 0.77 | KMT2A (0.35) | ADORA3ALDH1A1GAAHSD17B10PDGFRB | |
| SCHEMBL128876 | 0.76 | MEN1 (0.44) | RAC1ALDH1A1HSD17B10PDGFRBKDM4E | |
| SCHEMBL14927117 | 0.76 | SLC10A2 (0.44) | PDGFRBKDM4EMAPT | |
| SCHEMBL14927023 | 0.73 | FYN (0.41) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL127791 | 0.72 | RAC1 (0.52) | RAC1ALDH1A1GAAGRK6KDM4E | |
| SCHEMBL20739358 | 0.69 | BACE1 (0.32) | ADORA3ALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL151888 | 0.68 | SLC10A2 (0.46) | RAC1ALDH1A1GAAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933096-B2 | Antimicrobial agents | Rugers, The State University of New Jersey (US) | 2015-01-13 | — | — | US | disclosed |
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116278-A1 | ANTIMICROBIAL AGENTS | MRPL21, ARG1, RPP30 | RAC1 356/4885ADORA3 575/4885TUBB4A 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.