Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14928247 | 0.85 | CRHBP (0.53) | AAK1CRHBPCRHR2CYP19A1ALDH1A1 | |
| SCHEMBL30145522 | 0.85 | CRHBP (0.53) | AAK1CRHBPCRHR2CYP19A1ALDH1A1 | |
| SCHEMBL28156927 | 0.81 | AAK1 (0.52) | AAK1NPC1RAB9ACYP19A1ALDH1A1 | |
| SCHEMBL27844725 | 0.79 | ALDH1A1 (0.59) | NPC1RAB9AABCG2CRHBPCRHR2 | |
| SCHEMBL9197991 | 0.79 | AAK1 (0.60) | AAK1CYP19A1ALDH1A1TDP1MAPT | |
| SCHEMBL19541481 | 0.78 | CES2 (0.54) | NPC1RAB9AABCG2CRHBPCRHR2 | |
| SCHEMBL19541228 | 0.76 | MEN1 (0.50) | TP53NPC1RAB9ACRHBPCRHR2 | |
| SCHEMBL16919513 | 0.76 | ALDH1A1 (0.59) | AAK1TP53NPC1RAB9AABCG2 | |
| SCHEMBL22604036 | 0.74 | MAPK1 (0.62) | NPC1RAB9AABCG2ALDH1A1MAPT | |
| SCHEMBL14928233 | 0.74 | MEN1 (0.51) | AAK1CRHBPCRHR2CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828559-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| US-8828559-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-05-09 | — | — | US | disclosed |
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130113367-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | TELO2, ARL1, CRY1 | AAK1 2210/4885TP53 2919/4885NPC1 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.