Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | UMPS | P11172 | 3/20 | 0.43 |
| ▸ | IGF2R | P11717 | 4/20 | 0.39 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 2/20 | 0.38 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | ADSS2 | P30520 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722784 | 0.80 | FBP1 (0.48) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL18118157 | 0.76 | FBP1 (0.46) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL15305518 | 0.76 | FBP1 (0.46) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL18350026 | 0.76 | FBP1 (0.46) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL19679997 | 0.75 | FBP1 (0.48) | FBP1UMPSDNPH1ATICGART | |
| SCHEMBL14928570 | 0.75 | FBP1 (0.48) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL25624133 | 0.75 | FBP1 (0.48) | FBP1UMPSIGF2RDNPH1ATIC | |
| SCHEMBL14946101 | 0.72 | UMPS (0.52) | FBP1UMPSDNPH1ATICGART | |
| SCHEMBL17789093 | 0.72 | UMPS (0.52) | FBP1UMPSDNPH1ATICGART | |
| SCHEMBL15044550 | 0.72 | UMPS (0.52) | FBP1UMPSDNPH1ATICGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9428535-B2 | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof | MODERNA THERAPEUTICS, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-20130115272-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-09 | — | — | US | disclosed |