Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14930753 | 0.81 | CA2 (0.34) | — | |
| SCHEMBL14930749 | 0.77 | MEN1 (0.33) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL14930750 | 0.73 | — | — | |
| SCHEMBL363817 | 0.72 | ATM (0.44) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL11351266 | 0.68 | GABRA1 (0.50) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL19043212 | 0.67 | ATM (0.38) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL19361542 | 0.63 | AR (0.40) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL13845362 | 0.62 | CYP1A2 (0.33) | MEN1HSP90AA1KMT2AATM | |
| SCHEMBL365437 | 0.62 | GABRA1 (0.48) | KMT2A | |
| SCHEMBL23132307 | 0.62 | SIGMAR1 (0.42) | MEN1HSP90AA1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096791-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20130116464-A1 | METAL COMLEXES | MERK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |