SCHEMBL363817

SCHEMBL363817

C=Nc1c(C)cccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.44
MEN1 O00255 1/20 0.44
HSP90AA1 P07900 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2A6 P11509 2/20 0.43
CYP1A2 P05177 1/20 0.43
ACHE P22303 3/20 0.42
TSHR P16473 2/20 0.42
ALDH1A1 P00352 5/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL28852300 0.86 CYP2A6 (0.43) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL28182259 0.84 MEN1 (0.39) ATMMEN1HSP90AA1KMT2ATSHR
SCHEMBL19043212 0.83 ATM (0.38) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL13845362 0.81 CYP1A2 (0.33) ATMMEN1HSP90AA1KMT2ACYP1A2
SCHEMBL23132307 0.81 SIGMAR1 (0.42) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL11139239 0.79 GABRA1 (0.48) ATMMEN1HSP90AA1KMT2AALDH1A1
SCHEMBL11351266 0.79 GABRA1 (0.50) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL19361542 0.78 AR (0.40) ATMMEN1HSP90AA1KMT2AALDH1A1
SCHEMBL11441204 0.76 ALDH1A1 (0.33) ATMMEN1HSP90AA1KMT2ACYP2A6
SCHEMBL21386026 0.76 CYP2C9 (0.35) ATMMEN1HSP90AA1KMT2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2802566-B1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2016-03-16 EP claimed
US-9079862-B2 Process for preparing acetanilides BASF SE (DE) 2015-07-14 US claimed
US-20140364623-A1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2014-12-11 US claimed
EP-2802566-A1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2014-11-19 EP claimed
WO-2013104478-A1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2013-07-18 WO claimed
WO-2010051136-A1 METHOD FOR PREPARING POLYURETHANE UREA-CONTAINING FILMS PPG INDUSTRIES OHIO, INC. (US) 2010-05-06 WO claimed
CN-111499865-B Synthesis method of phosphorus-containing polyimide 湘潭大学 2022-04-26 CN disclosed
CN-114031519-A Method for synthesizing N-aryl imine 浙江工业大学 2022-02-11 CN disclosed
US-9772568-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-26 US disclosed
EP-2669338-B1 Coloring composition, ink for inkjet recording and inkjet recording method FUJIFILM CORP (JP) 2017-04-05 EP disclosed
EP-2802566-B1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2016-03-16 EP disclosed
EP-2802566-B1 PROCESS FOR PREPARING ACETANILIDES BASF SE (DE) 2016-03-16 EP disclosed
US-9079862-B2 Process for preparing acetanilides BASF SE (DE) 2015-07-14 US disclosed
EP-1311464-B1 MANUFACTURING PROCESS FOR ALPHA-OLEFINS DU PONT (US) 2007-09-05 EP disclosed
US-4340739-A CHEMICAL INTERMEDIATES IN THE PRODUCTION OF N-AZOLYLMETHYL-COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
EP-0013360-B1 N-SUBSTITUTED CARBOXYLIC ACID ANILIDES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE AS FUNGICIDES BASF Aktiengesellschaft (DE) 1982-04-07 EP disclosed
EP-0013361-B1 SUBSTITUTED N-HALOGENOMETHYL ANILIDES, PROCESS FOR THEIR PREPARATION AND USE BASF Aktiengesellschaft (DE) 1981-09-16 EP disclosed
EP-0013361-A2 Substituted N-halogenomethyl anilides, process for their preparation and use BASF Aktiengesellschaft (DE) 1980-07-23 EP disclosed
EP-0013360-A2 N-substituted carboxylic acid anilides, process for their preparation as well as their use as fungicides BASF Aktiengesellschaft (DE) 1980-07-23 EP disclosed
US-4159328-A INSECTICIDES, MITICIDES NIHON NOHYAKU CO., LTD. (JP) 1979-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140364623-A1 PROCESS FOR PREPARING ACETANILIDES HAX1, CYP4X1, HACL2 ATM 2477/4885MEN1 2053/4885HSP90AA1 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.