SCHEMBL14930766

SCHEMBL14930766

C=C(/C=C\C=C/C)NC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.34
CNR2 P34972 6/20 0.33
CNR1 P21554 4/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
CRBN Q96SW2 1/20 0.32
SOAT1 P35610 1/20 0.32
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18551018 0.84
SCHEMBL18726620 0.83 RAB9A (0.34) RAB9ACNR2CNR1PPARGPPARD
SCHEMBL20663294 0.82
SCHEMBL15293403 0.81 CRBN (0.41) CRBNTAS2R38
SCHEMBL19983010 0.80 CRBN (0.33) CRBNTAS2R38
SCHEMBL20442275 0.79 RAB9A (0.33) RAB9ACNR2CNR1PPARGPPARD
SCHEMBL27382484 0.76 CRBN (0.33) CRBNTAS2R38
SCHEMBL18404292 0.76 CNR2 (0.33) RAB9ACNR2CNR1PPARGPPARD
SCHEMBL13847434 0.75 MAPT (0.33) RAB9ACNR2CNR1PPARGPPARD
SCHEMBL24247970 0.74 CNR2 (0.33) RAB9ACNR2CNR1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023031775-A1 COMPOSITIONS FOR PREVENTING OR TREATING CHARCOT-MARIE-TOOTH DISEASE (CMT) CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2023-03-09 WO disclosed
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC 2017-01-12 US disclosed
US-20160024226-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE BIOMOLECULAR HOLDINGS LLC 2016-01-28 US disclosed
US-20130112106-A1 ENVIRONMENTALLY FRIENDLY CORROSION INHIBITOR APERGY ESP SYSTEMS, LLC 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024226-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, FCGR2A, VSIG8 RAB9A 3740/4885CNR2 2715/4885CNR1 2035/4885
US-20170008950-A1 HYBRID IMMUNOGLOBULIN CONTAINING NON-PEPTIDYL LINKAGE FCGR3B, SCLY, FCGR2A RAB9A 3370/4885CNR2 4510/4885CNR1 4407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.