Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.62 |
| ▸ | CTSL | P07711 | 5/20 | 0.45 |
| ▸ | CTSB | P07858 | 5/20 | 0.45 |
| ▸ | CTSH | P09668 | 2/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003112 | 0.84 | CTSK (0.59) | CTSKCTSLCTSBCTSHSLC15A1 | |
| SCHEMBL9572289 | 0.84 | CTSK (0.59) | CTSKCTSLCTSBCTSHSLC15A1 | |
| SCHEMBL6031204 | 0.84 | CTSK (0.59) | CTSKCTSLCTSBCTSHSLC15A1 | |
| SCHEMBL8972183 | 0.82 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL5712420 | 0.82 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8695376 | 0.82 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8387889 | 0.82 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL1783726 | 0.81 | CTSK (0.56) | CTSKCTSLCTSBCTSH | |
| SCHEMBL4292353 | 0.81 | CTSK (0.56) | CTSKCTSLCTSBCTSH | |
| SCHEMBL258985 | 0.81 | CTSK (0.56) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067415-A1 | IDENTIFICATION AND USE OF PROTEASE INHIBITORS TO TREAT OR PREVENT SICKLE CELL DISEASE | TUFTS UNIVERSITY (US) | 2013-05-10 | — | — | WO | disclosed |