Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | CTSH | P09668 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972183 | 1.00 | CTSK (0.57) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL8387889 | 1.00 | CTSK (0.57) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL18328801 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL1783728 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL1783726 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL15756119 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL231491 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL4292353 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL258985 | 0.99 | CTSK (0.56) | CTSKALDH1A1CTSLCTSBCTSH | |
| SCHEMBL9234715 | 0.92 | CTSK (0.52) | CTSKALDH1A1CTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714471-A | USEFUL IN INDICATING NEURODEGENERATIVE DISORDERS CHARACTERIZED BY DEPOSITION OF CEREBRAL AMYLOID | SIBIA NEUROSCIENCES, INC. (US) | 1998-02-03 | — | — | US | disclosed |