SCHEMBL8387889

SCHEMBL8387889

CCCC[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CTSK P43235 16/20 0.57
ALDH1A1 P00352 2/20 0.46
CTSL P07711 4/20 0.41
CTSB P07858 4/20 0.41
CTSH P09668 2/20 0.41
CTSS P25774 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8972183 1.00 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8695376 1.00 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL18328801 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783728 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783726 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL15756119 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL231491 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL4292353 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL258985 0.99 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL9234715 0.92 CTSK (0.52) CTSKALDH1A1CTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110129344-B Improved thymidine kinase gene 吉恩维沃公司 2024-06-18 CN disclosed
EP-0910632-A2 PRESENTATION OF ANTIGEN, INTRODUCED INTO THE CELLS BY STIMULATION OF MACROPINOCYTOSIS THE UNIVERSITY OF DUNDEE, UNIVERSITY COURT (GB) 1999-04-28 EP disclosed
US-5714471-A USEFUL IN INDICATING NEURODEGENERATIVE DISORDERS CHARACTERIZED BY DEPOSITION OF CEREBRAL AMYLOID SIBIA NEUROSCIENCES, INC. (US) 1998-02-03 US disclosed
WO-1997023607-A2 PRESENTATION OF ANTIGEN, INTRODUCED INTO CELLS BY STIMULATION OF MACROPINOCYTOSIS THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) 1997-07-03 WO disclosed