SCHEMBL258985

SCHEMBL258985

CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(C)=O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSK P43235 13/20 0.56
ALDH1A1 P00352 1/20 0.45
CTSL P07711 3/20 0.41
CTSB P07858 3/20 0.41
CTSH P09668 2/20 0.41
CTSS P25774 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
BIRC2 Q13490 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4292353 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL18328801 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783726 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL1783728 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL15756119 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL231491 1.00 CTSK (0.56) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8387889 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8972183 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL8695376 0.99 CTSK (0.57) CTSKALDH1A1CTSLCTSBCTSH
SCHEMBL9234715 0.93 CTSK (0.52) CTSKALDH1A1CTSLCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250281564-A1 DYSREGULATION OF NEUROPROTEASOMES BY APOE ISOFORMS DRIVES ENDOGENOUS TAU AGGREGATION UNIV COLUMBIA (US) 2025-09-11 US claimed
US-20250262268-A1 Methods and Compositions for Inhibiting Viral Infection NEW YORK UNIVERSITY 2025-08-21 US claimed
US-20250186486-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION BAYLOR COLLEGE OF MEDICINE (US) 2025-06-12 US claimed
CN-119942448-A Target person abnormal behavior prediction method based on AI 陕西公众信息产业有限公司 2025-05-06 CN claimed
US-20250114368-A1 COMPOSITIONS AND METHODS RELATING TO PEDIATRIC NEUROMUSCULAR DISEASES AND NEUROGENERATIVE DISORDERS ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO 2025-04-10 US claimed
CN-119758340-A High-precision positioning method based on 77GHZ vehicle millimeter wave radar 斯达领动智能科技(苏州)有限公司 2025-04-04 CN claimed
US-12233051-B2 Treating primary or idiopathic hyperoxaluria with small molecule inhibitors of lactate dehydrogenase VANDERBILT UNIVERSITY (US) 2025-02-25 US claimed
EP-4493166-A1 POTENTIATION OF DURABLE ANTITUMOR IMMUNITY BY MULTIFACTORIAL IMMUNE MODULATION Baylor College of Medicine (US) 2025-01-22 EP claimed
CN-119278032-A Enhancement of persistent antitumor immunity by multifactorial immunomodulation 贝勒医学院 2025-01-07 CN claimed
WO-2024118561-A2 DYSREGULATION OF NEUROPROTEASOMES BY APOE ISOFORMS DRIVES ENDOGENOUS TAU AGGREGATION THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-06-06 WO claimed
US-20150168419-A1 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2015-06-18 US claimed
US-20130295679-A1 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2013-11-07 US claimed
EP-2641092-A1 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT University College Cork - National University of Ireland, Cork (IE) 2013-09-25 EP claimed
WO-2012066057-A1 PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK (IE) 2012-05-24 WO claimed
EP-1342085-B1 NON-APOPTOTIC FORMS OF CELL DEATH AND METHODS OF MODULATION BURNHAM INST (US) 2009-09-30 EP claimed
WO-2002101012-A9 REGULATION OF TRANSGENE EXPRESSION FOLLOWING AAV TRANSDUCTION CHILDREN S HOSPITAL RES FOUNDA (US) 2003-12-18 WO claimed
US-20030003583-A1 Regulation of transgene expression following AAV transduction CHILDREN'S HOSPITAL RESEARCH FOUNDATION 2003-01-02 US claimed
WO-2002101012-A2 REGULATION OF TRANSGENE EXPRESSION FOLLOWING AAV TRANSDUCTION CHILDREN'S HOSPITAL RESEARCH FOUNDATION (US) 2002-12-19 WO claimed
US-20020111314-A1 Novel stimulation of gene expression and protein synthesis of heat shock protein 72/73 (Hsp 70) THE TRUSTEES OF COLUMBIA UNIVERSITY (US) 2002-08-15 US claimed
US-5942494-A Stimulation of gene expression and synthesis of heat shock protein 72/73 (HSP 70) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-08-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250281564-A1 DYSREGULATION OF NEUROPROTEASOMES BY APOE ISOFORMS DRIVES ENDOGENOUS TAU AGGREGATION MAPT, PSEN1, PSEN2 CTSK 617/4885ALDH1A1 4563/4885CTSL 1505/4885
US-12233051-B2 Treating primary or idiopathic hyperoxaluria with small molecule inhibitors of lactate dehydrogenase XDH, GLS, LDHA CTSK 1120/4885ALDH1A1 121/4885CTSL 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.