Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17278340 | 0.81 | HSD17B10 (0.31) | ALDH1A1MAPTHPGDHSD17B10KMT2A | |
| SCHEMBL4763054 | 0.67 | FPR1 (0.38) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL24771380 | 0.63 | EGFR (0.30) | — | |
| SCHEMBL299840 | 0.60 | HSPA1A (0.56) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL25615736 | 0.60 | DNMT1 (0.44) | ALDH1A1MAPTHSD17B10KMT2AMEN1 | |
| SCHEMBL21236807 | 0.60 | MEN1 (0.33) | ALDH1A1HPGDKMT2AMEN1GAA | |
| SCHEMBL16281050 | 0.60 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL28678587 | 0.59 | MGLL (0.50) | ALDH1A1PKMHPGDKMT2AMEN1 | |
| SCHEMBL23155078 | 0.58 | DDB1 (0.43) | ALDH1A1MAPTHPGDHSD17B10KMT2A | |
| SCHEMBL9857022 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773721-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| WO-2013064206-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |