Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934220 | 0.99 | ALDH1A1 (0.50) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL15208345 | 0.84 | SMN1; SMN2 (0.56) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL15208504 | 0.83 | HTT (0.54) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL14934261 | 0.82 | ALDH1A1 (0.55) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL14934258 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL15218943 | 0.80 | RXFP1 (0.52) | ALDH1A1LMNAGAASMN1; SMN2HTT | |
| SCHEMBL15209067 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1LMNAGAASMN1; SMN2MAPT | |
| SCHEMBL14934213 | 0.79 | PARP1 (0.42) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL15209795 | 0.79 | HCAR3 (0.46) | ALDH1A1GAASMN1; SMN2MAPTTDP1 | |
| SCHEMBL15208534 | 0.78 | HCAR3 (0.51) | ALDH1A1LMNAGAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| WO-2013064029-A1 | BENZOYLUREA DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2013-05-10 | — | — | WO | disclosed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |