Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208504 | 0.97 | HTT (0.54) | RXFP1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL15208345 | 0.96 | SMN1; SMN2 (0.56) | RXFP1GAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL15209063 | 0.88 | GAA (0.48) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL15209356 | 0.88 | L3MBTL1 (0.54) | GAAALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL15208595 | 0.88 | GAA (0.67) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| Hydrochloric Acid SCHEMBL15209122 | 0.87 | L3MBTL1 (0.53) | GAAALDH1A1SMN1; SMN2LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL15209798 | 0.87 | GAA (0.47) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL14934220 | 0.81 | ALDH1A1 (0.50) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL15208727 | 0.81 | ALDH1A1 (0.44) | GAAALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL14934216 | 0.80 | ALDH1A1 (0.52) | GAAALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946478-B2 | Benzamide derivative with anticancer activity and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| US-8946478-B2 | Benzamide derivative with anticancer activity and preparation method and use thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2015-02-03 | — | — | US | disclosed |
| EP-2636667-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2013-09-11 | — | — | EP | disclosed |
| US-20130225810-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2013-08-29 | — | — | US | disclosed |
| US-20130225810-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2013-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225810-A1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | HDAC5, TMBIM6, HDAC6 | RXFP1 4490/4885GAA 80/4885ALDH1A1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.