Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934261 | 0.99 | ALDH1A1 (0.55) | ALDH1A1LMNAPARP1GAAL3MBTL1 | |
| SCHEMBL14934220 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNAGAAL3MBTL1NPY1R | |
| SCHEMBL14934216 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNAGAAL3MBTL1NPY1R | |
| SCHEMBL28829330 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAL3MBTL1NPY1R | |
| SCHEMBL27901177 | 0.78 | PARP1 (0.69) | ALDH1A1LMNAPARP1SMN1; SMN2MAPT | |
| SCHEMBL15208952 | 0.78 | PARP1 (0.64) | ALDH1A1PARP1GAASMN1; SMN2TDP1 | |
| SCHEMBL14934251 | 0.76 | PARP1 (0.57) | ALDH1A1LMNAPARP1GAAL3MBTL1 | |
| SCHEMBL14934253 | 0.75 | PARP1 (0.54) | ALDH1A1LMNAPARP1GAAL3MBTL1 | |
| SCHEMBL14934211 | 0.75 | PARP1 (0.56) | ALDH1A1LMNAPARP1SMN1; SMN2MAPT | |
| SCHEMBL14934242 | 0.73 | PARP1 (0.54) | ALDH1A1LMNAPARP1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| WO-2013064029-A1 | BENZOYLUREA DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | 浙江海正药业股份有限公司 (CN) | 2013-05-10 | — | — | WO | disclosed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |