SCHEMBL14935151

SCHEMBL14935151

CCC(CC)(C(=O)OCc1ccc(Cl)cc1)C(=O)OCc1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
OPRK1 P41145 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
L3MBTL1 Q9Y468 4/20 0.45
MAPK1 P28482 1/20 0.45
PPARA Q07869 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
ABCB11 O95342 1/20 0.44
TSHR P16473 1/20 0.44
HTR2A P28223 1/20 0.44
PMP22 Q01453 1/20 0.44
ALDH1A1 P00352 5/20 0.43
MMP2 P08253 2/20 0.43
MMP1 P03956 1/20 0.43
MMP9 P14780 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419179 0.85 OPRK1 (0.49) MAOAMAOBOPRK1NPSR1MEN1
SCHEMBL14935068 0.83 ALDH1A1 (0.51) MAOAMAOBNPSR1MEN1MAPT
SCHEMBL1708845 0.82 CYP1A2 (0.54) MAOAMAOBOPRK1NPSR1MEN1
SCHEMBL6108042 0.82 ALDH1A1 (0.58) MAOBMEN1MAPTKMT2AL3MBTL1
SCHEMBL18671929 0.82 OPRK1 (0.47) MAOAMAOBOPRK1NPSR1MEN1
SCHEMBL28322756 0.81 SMN1; SMN2 (0.50) MEN1MAPTKMT2AL3MBTL1ALDH1A1
SCHEMBL6643065 0.79 NAMPT (0.46) MAPTKMT2AL3MBTL1ALDH1A1KDM4E
SCHEMBL38662035 0.79 MAOA (0.46) MAOAMAOBNPSR1MEN1MAPT
SCHEMBL11852547 0.78 MAOA (0.43) MAOAMAOBNPSR1MEN1MAPT
SCHEMBL8940532 0.78 MAOB (0.52) MAOAMAOBMAPTL3MBTL1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10197881-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2019-02-05 US disclosed
US-20170184936-A1 Complimentary Polymer Electrochromic Device ASHWIN-USHAS CORP INC (US) 2017-06-29 US disclosed
EP-2780762-B1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORP INC (US) 2017-06-28 EP disclosed
US-9594284-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2017-03-14 US disclosed
US-9274395-B2 Complimentary polymer electrochromic device ASHWIN-USHAS CORPORATION, INC. (US) 2016-03-01 US disclosed
US-20150275385-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN USHAS CORP INC (US) 2015-10-01 US disclosed
EP-2780762-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE Ashwin-Ushas Corporation, Inc. (US) 2014-09-24 EP disclosed
WO-2013074702-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-23 WO disclosed
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE ASHWIN-USHAS CORPORATION, INC. (US) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10197881-B2 Complimentary polymer electrochromic device PMS2, PARG, EED MAOA 1590/4885MAOB 1420/4885OPRK1 3435/4885
US-20130120821-A1 COMPLIMENTARY POLYMER ELECTROCHROMIC DEVICE PMS2, PARG, EED MAOA 1590/4885MAOB 1420/4885OPRK1 3435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.