Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | ERCC5 | P28715 | 4/20 | 0.65 |
| ▸ | FEN1 | P39748 | 4/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.55 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441329 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL28519783 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL5142646 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL440631 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| Silver SCHEMBL527868 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL5144868 | 0.95 | KMT2A (0.70) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL7860529 | 0.85 | KMT2A (0.61) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL28387528 | 0.84 | ERCC5 (0.69) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL15252116 | 0.84 | ERCC5 (0.69) | KMT2AMEN1CYP3A4HPGDMAPK1 | |
| SCHEMBL28413743 | 0.84 | ERCC5 (0.69) | KMT2AMEN1CYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2599840-B1 | SILVER INK COMPOSITION AND BASE MATERIAL | TOPPAN FORMS CO LTD (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9328254-B2 | Silver ink composition and substrate | TOPPAN FORMS CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| EP-2599840-A1 | SILVER INK COMPOSITION AND BASE MATERIAL | Toppan Forms Co., Ltd. (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20130121872-A1 | Silver Ink Composition and Substrate | TOPPAN FORMS CO., LTD. (JP) | 2013-05-16 | — | — | US | disclosed |