SCHEMBL14937109

SCHEMBL14937109

O=C(Oc1ccc2ccccc2c1)C1CC1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.87
▸ KMT2A Q03164 6/20 0.63
▸ MAPT P10636 4/20 0.63
▸ MEN1 O00255 3/20 0.63
▸ PDGFRB P09619 2/20 0.62
▸ PDGFRA P16234 2/20 0.62
▸ FABP7 O15540 1/20 0.59
▸ FABP3 P05413 1/20 0.59
▸ ELANE P08246 2/20 0.58
▸ TDP1 Q9NUW8 2/20 0.56
▸ HTT P42858 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ FAAH O00519 1/20 0.55
▸ EPHX1 P07099 1/20 0.55
▸ RAB9A P51151 1/20 0.54
▸ POLB P06746 2/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ CHRNA3 P32297 1/20 0.51
▸ GLA P06280 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051416 1.00 L3MBTL1 (0.87) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL1615379 0.94 L3MBTL1 (0.77) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL11829358 0.93 L3MBTL1 (0.75) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL13004851 0.92 L3MBTL1 (0.91) L3MBTL1KMT2AMAPTMEN1PDGFRB
Hydrochloric Acid SCHEMBL27535397 0.89 L3MBTL1 (0.75) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL18058689 0.84 KMT2A (0.85) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL18636251 0.84 L3MBTL1 (0.64) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL13004852 0.84 KMT2A (0.79) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL11827930 0.81 KMT2A (0.70) L3MBTL1KMT2AMAPTMEN1PDGFRB
SCHEMBL11823665 0.80 KMT2A (0.83) L3MBTL1KMT2AMAPTMEN1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822724-B2 Method for producing carboxylic acid amide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-02 — — US disclosed
EP-2599769-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE Sumitomo Chemical Company Limited (JP) 2013-06-05 — — EP disclosed
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE SUMITOMO CHEMICAL COMPANY, LIMITED 2013-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123505-A1 METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE HCAR2, NAAA, FAAH2 L3MBTL1 4136/4885KMT2A 390/4885MAPT 3830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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