Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306329 | 0.88 | ALOX15 (0.41) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| Bromide SCHEMBL1494095 | 0.86 | ALOX15 (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| Hydrochloric Acid SCHEMBL755483 | 0.86 | ALOX15 (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL1305671 | 0.80 | POLB (0.40) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL17893420 | 0.80 | ALDH1A1 (0.46) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| Hydrochloric Acid SCHEMBL18075817 | 0.79 | SMN1; SMN2 (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL1493761 | 0.79 | MGAM (0.39) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL1566652 | 0.76 | OPRM1 (0.40) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| SCHEMBL10151903 | 0.75 | SMN1; SMN2 (0.38) | OPRM1OPRD1OPRK1SMN1; SMN2SLC22A1 | |
| Trifluoroacetic Acid SCHEMBL28700412 | 0.74 | DPP4 (0.34) | OPRM1OPRD1OPRK1SMN1; SMN2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172444-A1 | METHOD FOR PURIFYING AMINOACETYLPYRROLIDINECARBONITRILE DERIVATIVE AND SALT THEREOF | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2332908-A1 | METHOD FOR PURIFYING AMINOACETYLPYRROLIDINECARBONITRILE DERIVATIVE AND SALT THEREOF | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-7915427-B2 | Process for producing aminoacetyl pyrrolidine carbonitrile derivative and intermediate for production thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | KYORIN PHARMACEUTICALS CO., LTD. (JP) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048454-A1 | Process for Producing Aminoacetyl Pyrrolidine Carbonitrile Derivative and Intermediate for Production Thereof | CBR3, CPS1, CBR1 | OPRM1 3573/4885OPRD1 2431/4885OPRK1 3469/4885 |
| US-20110172444-A1 | METHOD FOR PURIFYING AMINOACETYLPYRROLIDINECARBONITRILE DERIVATIVE AND SALT THEREOF | DPP4, DPP7, DPP9 | OPRM1 3721/4885OPRD1 2381/4885OPRK1 3767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.