Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606677 | 0.84 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL9656226 | 0.81 | POLB (0.69) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL9656234 | 0.81 | POLB (0.69) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14938455 | 0.79 | MAPT (0.64) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14942143 | 0.79 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14938452 | 0.76 | POLB (0.68) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14950223 | 0.75 | POLB (0.58) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL30616243 | 0.74 | ALDH1A1 (0.50) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL14938481 | 0.74 | MAPK1 (0.55) | RAB9ANPC1SMN1; SMN2POLBKMT2A | |
| SCHEMBL5943067 | 0.73 | KMT2A (0.76) | RAB9ANPC1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |