Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656226 | 1.00 | POLB (0.69) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14938452 | 0.85 | POLB (0.68) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11606677 | 0.83 | RAB9A (0.74) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14950223 | 0.81 | POLB (0.58) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14938448 | 0.81 | RAB9A (0.65) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14942143 | 0.79 | RAB9A (1.00) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL942207 | 0.78 | ALDH1A1 (0.64) | POLBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL940739 | 0.78 | ALDH1A1 (0.64) | POLBRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL564406 | 0.77 | POLB (0.66) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL119577 | 0.77 | POLB (0.66) | POLBKMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299974-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0299974-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006127-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |