Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938455 | 0.87 | MAPT (0.64) | MAPK1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL14938527 | 0.81 | RAD51 (0.54) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14938450 | 0.79 | MAPK1 (0.58) | MAPK1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14938483 | 0.77 | RAB9A (0.56) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5706102 | 0.76 | RAB9A (0.57) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14938448 | 0.74 | RAB9A (0.65) | RAB9AKMT2AMAPTALDH1A1POLB | |
| SCHEMBL12549885 | 0.74 | RAB9A (0.88) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30616243 | 0.73 | ALDH1A1 (0.50) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12186261 | 0.73 | MAPT (0.70) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14938458 | 0.71 | ALDH1A1 (0.53) | RAB9AMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |