Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | GCGR | P47871 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925015 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL14938584 | 0.80 | MAPT (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL14938583 | 0.80 | MAPT (0.56) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL14938463 | 0.80 | LMNA (0.58) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL14938467 | 0.80 | LMNA (0.58) | ALDH1A1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL4816435 | 0.80 | MEN1 (0.64) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL4816442 | 0.80 | MEN1 (0.64) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL32675200 | 0.78 | GCGR (0.82) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL30826056 | 0.78 | GCGR (0.82) | ALDH1A1LMNAF2GCGRMEN1 | |
| SCHEMBL13321124 | 0.78 | GCGR (0.82) | ALDH1A1LMNAF2GCGRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |