Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938467 | 1.00 | LMNA (0.58) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14938583 | 0.82 | MAPT (0.56) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14938584 | 0.82 | MAPT (0.56) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14938497 | 0.80 | LMNA (0.62) | LMNANPC1MAPTKMT2AMEN1 | |
| SCHEMBL14938495 | 0.80 | LMNA (0.62) | LMNANPC1MAPTKMT2AMEN1 | |
| SCHEMBL14938489 | 0.80 | ALDH1A1 (0.58) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14938438 | 0.80 | RAB9A (0.63) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL14938440 | 0.80 | RAB9A (0.63) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL20834535 | 0.79 | DUSP3 (0.66) | LMNANPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL17560977 | 0.79 | DUSP3 (0.66) | LMNANPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |