Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938584 | 1.00 | MAPT (0.56) | MAPTALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL22925028 | 0.83 | MAPT (0.60) | MAPTALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL14938467 | 0.82 | LMNA (0.58) | MAPTALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14938463 | 0.82 | LMNA (0.58) | MAPTALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14938495 | 0.80 | LMNA (0.62) | MAPTPOLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL14938489 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1CYP1A2CYP2C19POLB | |
| SCHEMBL14938497 | 0.80 | LMNA (0.62) | MAPTPOLBKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL14938440 | 0.80 | RAB9A (0.63) | MAPTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL14938438 | 0.80 | RAB9A (0.63) | MAPTALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL13475710 | 0.77 | KDM1A (0.62) | MAPTALDH1A1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013067646-A1 | PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS | UNIVERSITY OF OTTAWA (CA) | 2013-05-16 | — | — | WO | disclosed |