SCHEMBL14938501

SCHEMBL14938501

O=C(O)NN=C(c1ccccc1)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
RAB9A P51151 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
NPSR1 Q6W5P4 1/20 0.54
BCHE P06276 1/20 0.54
CTSL P07711 4/20 0.53
CTSB P07858 1/20 0.53
CTSK P43235 1/20 0.53
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
AGTR1 P30556 1/20 0.50
GSTA1 P08263 1/20 0.50
FAAH O00519 1/20 0.49
MGLL Q99685 1/20 0.49
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9768852 0.89 BCHE (0.67) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL22649382 0.86 BCHE (0.64) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL1562723 0.84 GSTA1 (0.68) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
Diphenylsemicarbazone SCHEMBL29448015 0.83 ALDH1A1 (0.67) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL5998679 0.83 ALDH1A1 (0.61) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL14938560 0.78 MAPT (0.78) ALDH1A1RAB9ASMN1; SMN2NPSR1KDM4E
SCHEMBL12629713 0.78 ALDH1A1 (0.53) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL2599808 0.78 ALDH1A1 (0.56) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL6441842 0.78 ALDH1A1 (0.56) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE
SCHEMBL10542963 0.78 ALDH1A1 (1.00) ALDH1A1RAB9ASMN1; SMN2NPSR1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013067646-A1 PROCESS FOR THE SYNTHESIS OF BETA-AMINOCARBONYLS UNIVERSITY OF OTTAWA (CA) 2013-05-16 WO disclosed