Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.55 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938501 | 0.89 | ALDH1A1 (0.63) | BCHEPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6687709 | 0.88 | GAA (0.66) | BCHEPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL14413395 | 0.88 | GAA (0.66) | BCHEPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL22649382 | 0.77 | BCHE (0.64) | BCHEPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9768867 | 0.76 | NPC1 (0.61) | BCHEKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL9768862 | 0.76 | NPC1 (0.61) | BCHEKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL9768608 | 0.76 | TP53 (0.53) | POLBKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9768607 | 0.76 | TP53 (0.53) | POLBKMT2AMEN1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9769045 | 0.75 | NPC1 (0.60) | BCHEKMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL9769046 | 0.75 | NPC1 (0.60) | BCHEKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |