SCHEMBL14938792

SCHEMBL14938792

CCOc1ccc(Cc2cc(Br)ccc2Cl)cc1.[MgH2]

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 17/20 0.52
SLC5A1 P13866 10/20 0.51
ADRA2A P08913 1/20 0.49
SLC5A11 Q8WWX8 1/20 0.49
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386304 0.98 SLC5A2 (0.53) SLC5A2SLC5A1ADRA2ASLC5A11ALDH1A1
SCHEMBL38150 0.98 SLC5A2 (0.53) SLC5A2SLC5A1ADRA2ASLC5A11ALDH1A1
SCHEMBL16608734 0.87 PKM (0.46) SLC5A2SLC5A1
SCHEMBL3680232 0.87 SLC5A2 (0.52) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL10211827 0.86 SLC5A2 (0.44) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL38651021 0.85 L3MBTL1 (0.44) SLC5A2SLC5A1
SCHEMBL27368089 0.85 L3MBTL1 (0.44) SLC5A2SLC5A1
SCHEMBL15397883 0.84 HTR2A (0.42) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL3680551 0.84 SLC5A2 (0.52) SLC5A2SLC5A1ADRA2ASLC5A11ALDH1A1
SCHEMBL18418928 0.83 DHFR (0.46) SLC5A2SLC5A1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703772-B2 Processes for the preparation of SGLT-2 inhibitors, intermediates thereof EMMENNAR PHARMA PRIVATE LIMITED (IN) 2020-07-07 US disclosed
US-20180346502-A1 Processes for the Preparation of SGLT-2 Inhibitors, Intermediates Thereof EMMENNAR PHARMA PRIVATE LIMITED (IN) 2018-12-06 US disclosed
EP-2776449-B1 PROCESS FOR THE PREPARATION OF BETA-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN LTD (TW) 2017-08-02 EP disclosed
US-8952139-B2 Process for the preparation of β-C-aryl glucosides SCINOPHARM TAIWAN, LTD (TW) 2015-02-10 US disclosed
EP-2776449-A2 PROCESS FOR THE PREPARATION OF beta-C-ARYL GLUCOSIDES Scinopharm Taiwan Ltd. (TW) 2014-09-17 EP disclosed
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SCINOPHARM TAIWAN, LTD. (TW) 2014-05-08 US disclosed
WO-2013068850-A2 PROCESS FOR THE PREPARATION OF β-C-ARYL GLUCOSIDES SCINOPHARM TAIWAN, LTD. (NA) 2013-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128595-A1 Process for the Preparation of ß-C-Aryl Glucosides SLC5A2, SLC5A1, UGGT1 SLC5A2 1/4885SLC5A1 2/4885ADRA2A 672/4885
US-10703772-B2 Processes for the preparation of SGLT-2 inhibitors, intermediates thereof SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885ADRA2A 2409/4885
US-20180346502-A1 Processes for the Preparation of SGLT-2 Inhibitors, Intermediates Thereof SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885ADRA2A 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.