Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939620 | 0.83 | NPSR1 (0.68) | NPSR1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL14940377 | 0.83 | NPSR1 (0.74) | NPSR1SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL14938779 | 0.81 | NPSR1 (0.65) | NPSR1OPRM1SIGMAR1MAPTMEN1 | |
| SCHEMBL14939755 | 0.79 | NPSR1 (0.57) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14939617 | 0.78 | NPSR1 (1.00) | NPSR1SIGMAR1MAPTDRD2LMNA | |
| SCHEMBL14939244 | 0.77 | NPSR1 (0.71) | NPSR1MAPTHTR7KMT2ALMNA | |
| SCHEMBL13150855 | 0.77 | HTR7 (0.55) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL14938987 | 0.77 | NPSR1 (0.85) | NPSR1SIGMAR1MAPTCHRM2DRD4 | |
| SCHEMBL14939520 | 0.76 | NPSR1 (0.57) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14939794 | 0.76 | NPSR1 (0.56) | NPSR1MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |