Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565240 | 0.75 | NPC1 (0.42) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL9831258 | 0.73 | CYP2C19 (0.51) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL9831681 | 0.72 | MEN1 (0.49) | ALDH1A1KDM4EHTTKMT2AMEN1 | |
| SCHEMBL4639985 | 0.71 | NPC1 (0.40) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL13437757 | 0.70 | LMNA (0.50) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL14939122 | 0.68 | ACHE (0.50) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL9831214 | 0.68 | KDM4E (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10967640 | 0.66 | LMNA (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL5469942 | 0.66 | KMT2A (0.64) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL2564341 | 0.66 | NPC1 (0.42) | ALDH1A1KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |