Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938940 | 0.86 | NPSR1 (0.49) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL14939574 | 0.84 | MAPT (0.41) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL14938934 | 0.83 | LMNA (0.38) | NPSR1LMNAHTTL3MBTL1UTS2R | |
| SCHEMBL14939544 | 0.81 | CA1 (0.37) | L3MBTL1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL14939222 | 0.81 | PARK7 (0.39) | ADAM17 | |
| SCHEMBL14939606 | 0.80 | NPSR1 (0.36) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL14939739 | 0.76 | NPSR1 (0.40) | NPSR1LMNAHTTL3MBTL1HTR2A | |
| SCHEMBL14939457 | 0.75 | NPSR1 (0.49) | NPSR1LMNAHTTL3MBTL1UTS2R | |
| SCHEMBL14939329 | 0.74 | KDM1A (0.37) | HTR2AHTR2CHTR2BMAOAMAOB | |
| SCHEMBL14939783 | 0.74 | CASP6 (0.40) | NPSR1LMNAHTTL3MBTL1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |