Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964279 | 0.89 | KMT2A (0.56) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL7444314 | 0.86 | CA1 (0.51) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL27176635 | 0.86 | PKM (0.54) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL641594 | 0.86 | CES1 (0.55) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL29118847 | 0.82 | ALDH1A1 (0.65) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL30737530 | 0.82 | POLB (0.60) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL3653048 | 0.82 | KEAP1 (0.59) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL29118833 | 0.82 | PGR (0.65) | KEAP1KMT2APTPN2PTPN1PTPN5 | |
| SCHEMBL4067674 | 0.82 | PGR (0.56) | KMT2ACA1CA2HTTMEN1 | |
| SCHEMBL27176660 | 0.82 | ALDH1A1 (0.53) | KEAP1KMT2APTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776488-A1 | HARDENERS FOR EPOXY RESIN COATINGS | Sika Technology AG (CH) | 2014-09-17 | — | — | EP | disclosed |
| EP-2776486-A1 | HARDENERS FOR EPOXY RESINS, WHICH COMPRISE PYRIDINYL GROUPS | Sika Technology AG (CH) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068506-A1 | HARDENERS FOR EPOXY RESINS, WHICH COMPRISE PYRIDINYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-05-16 | — | — | WO | disclosed |
| WO-2013068501-A1 | HARDENERS FOR EPOXY RESIN COATINGS | SIKA TECHNOLOGY AG (CH) | 2013-05-16 | — | — | WO | disclosed |