Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271341 | 0.70 | ALDH1A1 (0.42) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| Ammonia Solution, Strong SCHEMBL6402318 | 0.69 | ALDH1A1 (0.41) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| SCHEMBL6816877 | 0.67 | ALDH3A1 (0.58) | ALDH3A1ALDH1A3ALDH1A1GAAMAPT | |
| SCHEMBL14964149 | 0.67 | ALDH1A1 (0.39) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| SCHEMBL15263993 | 0.64 | ALDH3A1 (0.50) | ALDH3A1ALDH1A3ALDH1A1GAAMAPT | |
| SCHEMBL6080870 | 0.63 | PRKCI (0.47) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| SCHEMBL17774772 | 0.63 | HCAR3 (0.40) | ALDH3A1ALDH1A3ALDH1A1PRKCIGAA | |
| Hydrochloric Acid SCHEMBL9168202 | 0.62 | ACHE (0.49) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| SCHEMBL27532128 | 0.62 | PRKCI (0.39) | ALDH3A1ALDH1A3ALDH1A1PRKCIACHE | |
| SCHEMBL792483 | 0.62 | PRKCI (0.39) | ALDH1A1PRKCIACHEGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283024-B1 | 4-ARYL-2-ANILINO-PYRIMIDINES AS PLK KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-05-15 | — | — | EP | disclosed |