Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944696 | 0.73 | TLR7 (0.55) | — | |
| SCHEMBL19423898 | 0.58 | GSK3B (0.32) | — | |
| SCHEMBL8447171 | 0.57 | HPRT1 (0.57) | — | |
| SCHEMBL14944690 | 0.56 | TLR7 (0.59) | — | |
| SCHEMBL18322752 | 0.54 | KDM5B (0.37) | — | |
| SCHEMBL25857668 | 0.53 | KDM4E (0.42) | PDE8B | |
| SCHEMBL3478591 | 0.53 | NOS1 (0.35) | — | |
| SCHEMBL23123541 | 0.52 | HTR6 (0.36) | — | |
| SCHEMBL3322156 | 0.52 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL18277811 | 0.51 | KDM5B (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |