Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073556 | 1.00 | ACE (0.35) | ACECYP2C19GABRR1CYP1A2CYP2D6 | |
| SCHEMBL22613896 | 0.98 | CYP2C19 (0.33) | ACECYP2C19GABRR1CYP1A2CYP2D6 | |
| SCHEMBL22695503 | 0.87 | CHRNB2 (0.41) | — | |
| SCHEMBL5353331 | 0.83 | ACE (0.41) | ACECYP2C19GABRR1SLC1A2SLC1A1 | |
| SCHEMBL10299221 | 0.79 | BTK (0.39) | ACEGABRR1GABRPGABRDGABRA1 | |
| SCHEMBL15725229 | 0.79 | BTK (0.39) | ACEGABRR1GABRPGABRDGABRA1 | |
| SCHEMBL25808412 | 0.78 | — | — | |
| SCHEMBL5360064 | 0.77 | LMNA (0.40) | ACECYP2C19APLNRGABRPGABRD | |
| SCHEMBL19626326 | 0.77 | LMNA (0.40) | ACECYP2C19APLNRGABRPGABRD | |
| SCHEMBL23366184 | 0.74 | CYP2C19 (0.50) | ACECYP2C19GABRR1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264822-A1 | ADHESIVE AGENT | DAICEL CORPORATION (JP) | 2016-09-15 | — | — | US | disclosed |
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |