Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15725229 | 1.00 | BTK (0.39) | BTKANPEPACETSHRSLC6A1 | |
| SCHEMBL5353331 | 0.88 | ACE (0.41) | BTKACETSHRLMNAGABRR1 | |
| SCHEMBL24687706 | 0.83 | BTK (0.38) | BTKANPEPACETSHRSLC6A1 | |
| SCHEMBL24687493 | 0.83 | BTK (0.38) | BTKANPEPACETSHRSLC6A1 | |
| SCHEMBL22613896 | 0.81 | CYP2C19 (0.33) | ACETSHRSLC6A11SLC6A13GABRR1 | |
| SCHEMBL14944735 | 0.79 | ACE (0.35) | ACETSHRGABRR1GABRPGABRD | |
| SCHEMBL10073556 | 0.79 | ACE (0.35) | ACETSHRGABRR1GABRPGABRD | |
| SCHEMBL14425477 | 0.76 | BTK (0.45) | BTKANPEPACETSHRSLC6A1 | |
| SCHEMBL14042369 | 0.76 | BTK (0.45) | BTKANPEPACETSHRSLC6A1 | |
| SCHEMBL504043 | 0.76 | BTK (0.45) | BTKANPEPACETSHRSLC6A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780961-B2 | Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof | ZHEJIANG UNIVERSITY (CN) | 2023-10-10 | — | — | US | disclosed |
| US-20150291576-A1 | COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2015-10-15 | — | — | US | disclosed |
| US-9051452-B2 | Polymer compositions for temporary bonding | PROMERUS, LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-9029531-B2 | Compounds and their methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20140142081-A1 | COMPOUNDS AND THEIR METHODS OF USE | AGIOS PHARMACEUTICALS, INC (US) | 2014-05-22 | — | — | US | disclosed |
| US-8633259-B2 | Polymer compositions for temporary bonding | PROMERUS, LLC (US) | 2014-01-21 | — | — | US | disclosed |
| US-20120172479-A1 | POLYMER COMPOSITIONS FOR TEMPORARY BONDING | PROMERUS LLC (US) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291576-A1 | COMPOUNDS AND THEIR METHODS OF USE | GLS, GLS2, GLUL | BTK 2545/4885ANPEP 386/4885ACE 158/4885 |
| US-11780961-B2 | Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof | DUOX1, SOD1, DUOX2 | BTK 987/4885ANPEP 1179/4885ACE 1277/4885 |
| US-20140142081-A1 | COMPOUNDS AND THEIR METHODS OF USE | GLS, GLS2, GLUL | BTK 2857/4885ANPEP 328/4885ACE 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.