SCHEMBL5360064

SCHEMBL5360064

O=COC1CCC(C(=O)O)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
PLG P00747 1/20 0.40
PLAT P00750 1/20 0.40
TSHR P16473 2/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39
GABRE P78334 1/20 0.39
PMP22 Q01453 1/20 0.39
GABRA6 Q16445 1/20 0.39
GABRG1 Q8N1C3 1/20 0.39
GABRG3 Q99928 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19626326 1.00 LMNA (0.40) LMNAPLGPLATTSHRGABRP
SCHEMBL12733071 0.94 PLG (0.36) LMNAPLGPLATTSHRGABRP
SCHEMBL19829377 0.89 PLG (0.46) LMNAPLGPLATTSHRGABRP
SCHEMBL14867500 0.89 PLG (0.46) LMNAPLGPLATTSHRGABRP
SCHEMBL5353331 0.87 ACE (0.41) LMNAPLGPLATTSHRGABRP
SCHEMBL17755914 0.82 CYP2C19 (0.35) LMNAPLGPLATTSHRGABRP
SCHEMBL23081736 0.80 HPGD (0.33)
SCHEMBL98197 0.80
SCHEMBL899641 0.80 HPGD (0.33)
SCHEMBL22613896 0.79 CYP2C19 (0.33) TSHRGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof ZHEJIANG UNIVERSITY (CN) 2023-10-10 US disclosed
CN-105517574-B The combination product of hepatitis C virus inhibitors 百时美施贵宝公司 2019-01-18 CN disclosed
CN-104788297-B Liquid-crystal compounds containing difluoromethylenedioconnecting and combinations thereof thing and application 江苏和成显示科技股份有限公司 2016-08-17 CN disclosed
CN-105517574-A Combinations of hepatitis c virus inhibitors BRISTOL MYERS SQUIBB CO 2016-04-20 CN disclosed
US-9250525-B2 Resist underlayer film-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-02-02 US disclosed
US-20150362838-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL IND LTD (JP) 2015-12-17 US disclosed
US-9212255-B2 Resist underlayer film-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-15 US disclosed
US-9195137-B2 Composition for forming highly adhesive resist underlayer film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-24 US disclosed
US-9051452-B2 Polymer compositions for temporary bonding PROMERUS, LLC (US) 2015-06-09 US disclosed
US-20150087155-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-03-26 US disclosed
US-20080268371-A1 Polyester, polyurethane, polyether, polyamide, polyurea formed by a monomer containing two imine groups in the back bone and two end groups containing OH, NR2H, COOH, COCL, COOR, NCO and NCS group polymerized with other monomers; a photolatent or heat latent catalyst such as onium compounds, triazines FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080199691-A1 POLYMERIZABLE COMPOSITION, TACKY MATERIAL, AND ADHESIVE FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080199691-A1 POLYMERIZABLE COMPOSITION, TACKY MATERIAL, AND ADHESIVE FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080200581-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCING CURED COATING FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080200581-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCING CURED COATING FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-7202016-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2007-04-10 US disclosed
US-20050214680-A1 Radiation-sensitive resin composition MIYAJI MASAAKI 2005-09-29 US disclosed
US-6933094-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-08-23 US disclosed
US-20020058201-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-05-16 US disclosed
EP-1193558-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2002-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780961-B2 Organic metal-free catalysts with electrophilic and nucleophilic dual-functions, preparation methods of making the same, and uses thereof DUOX1, SOD1, DUOX2 LMNA 4262/4885PLG 3139/4885PLAT 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.