Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | PGK1 | P00558 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1494485 | 0.89 | KDM4E (0.69) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL23710624 | 0.89 | KDM4E (0.69) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL1494490 | 0.89 | KDM4E (0.69) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL29471286 | 0.89 | KDM4E (0.69) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL3470176 | 0.81 | FBP1 (0.64) | ADORA1NT5E | |
| SCHEMBL9153707 | 0.81 | NT5E (0.64) | SLC29A1LMNACYP2C19ADORA3ADORA1 | |
| SCHEMBL8970966 | 0.79 | ADORA3 (0.60) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL8970975 | 0.79 | ADORA3 (0.60) | KDM4EPKMSLC29A1LMNAGMNN | |
| SCHEMBL9153207 | 0.79 | ADRB1 (0.52) | LMNATP53DNMT1HTTHBB | |
| SCHEMBL9153212 | 0.79 | ADRB1 (0.52) | LMNATP53DNMT1HTTHBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449664-A | Nucleosides | SYNTEX (U.S.A.) INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0457326-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |