Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650972 | 0.81 | TDP1 (0.57) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL28655184 | 0.81 | TDP1 (0.63) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL12783352 | 0.81 | ACE (0.70) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL28650975 | 0.80 | CTSK (0.56) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL18215088 | 0.80 | CTSK (0.56) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL29758964 | 0.80 | CTSK (0.56) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL17278349 | 0.79 | ACE (0.68) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL17037427 | 0.78 | ACE (0.67) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL10422997 | 0.78 | ACE (0.67) | HPGDACETDP1NOTUMKMT2A | |
| SCHEMBL9512049 | 0.78 | ACE (0.67) | HPGDACETDP1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2019-07-02 | — | — | US | disclosed |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HPGD 564/4885ACE 736/4885TDP1 2158/4885 |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HPGD 564/4885ACE 736/4885TDP1 2158/4885 |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HPGD 564/4885ACE 736/4885TDP1 2158/4885 |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | HPGD 564/4885ACE 736/4885TDP1 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.