SCHEMBL14947847

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14947843	0.88	ALDH1A1 (0.52)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL14950786	0.87	ALDH1A1 (0.53)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL14950977	0.83	ALDH1A1 (0.53)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL7734709	0.79	ALDH1A1 (0.68)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL14947835	0.78	KMT2A (0.39)	ALDH1A1MAPK1CYP3A4LMNASMN1; SMN2
	SCHEMBL19809131	0.74	ALDH1A1 (0.55)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL3697616	0.72	ALDH1A1 (0.58)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL1500563	0.72	ALDH1A1 (0.65)	ALDH1A1TSHRMAPK1CYP3A4CA2
	SCHEMBL9581688	0.69	MAPT (0.54)	ALDH1A1LMNASMN1; SMN2POLBMAPT
	SCHEMBL22981	0.69	MEN1 (0.52)	ALDH1A1MAPK1LMNASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.