SCHEMBL14947879

SCHEMBL14947879

c1ccc(-n2c(-c3cccc(-c4cccc(-c5nc6ncccc6n5-c5ccccc5)c4)c3)nc3ncccc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
BACE1 P56817 1/20 0.50
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
RXFP1 Q9HBX9 2/20 0.39
BRD4 O60885 1/20 0.39
APOBEC3G Q9HC16 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
GRM5 P41594 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15197423 0.91 ESR1 (0.50) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL10247452 0.91 KMT2A (0.64) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL18082488 0.88 AKT1 (0.47) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL14947869 0.88 KMT2A (0.59) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL18875281 0.86 KMT2A (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL19961706 0.86 KMT2A (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL26855425 0.85 ALDH1A1 (0.48) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL15747069 0.82 KMT2A (0.54) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL18999467 0.81 KMT2A (0.47) KMT2ABACE1ALDH1A1TSHRCYP2C19
SCHEMBL15460301 0.80 KMT2A (0.41) KMT2ABACE1ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LIMITED (IE) 2024-01-25 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2023-10-24 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744144-B2 Organic electroluminescent element, light-emitting material therefor, light emitting device, display device, and illumination device UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element UDC IRELAND LIMITED (IE) 2023-01-24 US disclosed
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element UDC IRELAND LIMITED (IE) 2022-10-20 US disclosed
US-11171293-B2 Organic electroluminescent element, material for organic electroluminescent element, light emitting device, display device and lighting device each using said element, and compound used for said element UDC IRELAND LIMITED (IE) 2021-11-09 US disclosed
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device UDC IRELAND LTD (IE) 2021-08-12 US disclosed
US-20140291660-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element and Light Emitting Device, Display Device, and Illumination Device, Each Employing Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20140291660-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element and Light Emitting Device, Display Device, and Illumination Device, Each Employing Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20140291652-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAID ELEMENT UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20140291652-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND LIGHT-EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE USING SAID ELEMENT UDC IRELAND LIMITED (IE) 2014-10-02 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130264547-A1 MATERIALS FOR AN ORGANIC ELECTROLUMINESCENCE ELEMENT, ELECTROLUMINESCENT, DISPLAY AND ILLUMINATING DEVICES USING THE ELEMENTS UDC IRELAND LIMITED (IE) 2013-10-10 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element UDC IRELAND LIMITED (IE) 2013-05-23 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element UDC IRELAND LIMITED (IE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336752-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element L1CAM, NR2E3, OR10J3 KMT2A 1056/4885BACE1 846/4885ALDH1A1 224/4885
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element L1CAM, RER1, H1-0 KMT2A 3861/4885BACE1 892/4885ALDH1A1 203/4885
US-20130126835-A1 Organic Electroluminescent Element, Compound for Use in the Element, and Light Emitting Device, Display Device, and Illumination Device Using the Element L1CAM, RER1, H1-0 KMT2A 3861/4885BACE1 892/4885ALDH1A1 203/4885
US-20210249611-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 KMT2A 3600/4885BACE1 3308/4885ALDH1A1 981/4885
US-20130119359-A1 Organic Electroluminescent Element, Material for Organic Electroluminescent Element, and Light Emitting Device, Display Device and Illumination Device Each Using the Element L1CAM, ZYX, H1-0 KMT2A 1405/4885BACE1 1543/4885ALDH1A1 326/4885
US-11171293-B2 Organic electroluminescent element, material for organic electroluminescent element, light emitting device, display device and lighting device each using said element, and compound used for said element L1CAM, OR10J3, INTS9 KMT2A 1465/4885BACE1 1023/4885ALDH1A1 211/4885
US-11800798-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device TMEM109, SLC39A11, SLC39A14 KMT2A 3600/4885BACE1 3308/4885ALDH1A1 981/4885
US-20240032421-A1 Charge Transporting Material, Organic Electroluminescent Element, Light Emitting Device, Display Device And Illumination Device TMEM109, SLC39A11, SLC39A14 KMT2A 3600/4885BACE1 3308/4885ALDH1A1 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.