SCHEMBL14948207

SCHEMBL14948207

C=Cc1ccc2cc(N(c3ccccc3)c3ccc4c(c3)C(C)(C)c3ccccc3-4)ccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.35
MLNR O43193 1/20 0.31
NR1I2 O75469 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRB1 P08588 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM3 P20309 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2602462 0.91 PDK2 (0.39) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL2602496 0.89 PDK2 (0.37) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL15977004 0.89 PDK2 (0.35) PDK2
SCHEMBL14340230 0.89 PDK2 (0.42) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL13414351 0.88 PDK2 (0.40) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL14948226 0.88
SCHEMBL12925274 0.88 PDK2 (0.35) PDK2MLNRNR1I2CHRM2ADRB1
SCHEMBL5031008 0.87 ALDH1A1 (0.37) PDK2
SCHEMBL13358033 0.87 RELA (0.41) PDK2
SCHEMBL13358442 0.87 RELA (0.41) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9288869-B2 Styryl-based compound, composition containing styryl-based compound, and organic light emitting diode including styryl-based compound SAMSUNG DISPLAY CO., LTD. (KR) 2016-03-15 US disclosed
US-20130119355-A1 STYRYL-BASED COMPOUND, COMPOSITION CONTAINING STYRYL-BASED COMPOUND, AND ORGANIC LIGHT EMITTING DIODE INCLUDING STYRYL-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2013-05-16 US disclosed
US-20130119355-A1 STYRYL-BASED COMPOUND, COMPOSITION CONTAINING STYRYL-BASED COMPOUND, AND ORGANIC LIGHT EMITTING DIODE INCLUDING STYRYL-BASED COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130119355-A1 STYRYL-BASED COMPOUND, COMPOSITION CONTAINING STYRYL-BASED COMPOUND, AND ORGANIC LIGHT EMITTING DIODE INCLUDING STYRYL-BASED COMPOUND OCIAD1, MAP1LC3B, ELOVL1 PDK2 1317/4885MLNR 4728/4885NR1I2 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.