SCHEMBL14948359

SCHEMBL14948359

CCCCCCC[PH](CCCCCC)(CCCCCC)Cc1cc(N(c2ccccc2)c2ccc(C)cc2)ccc1C

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
PAX8 Q06710 2/20 0.33
JAK2 O60674 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
GPX4 P36969 1/20 0.33
CYP2C19 P33261 1/20 0.31
TACR1 P25103 1/20 0.31
LIPE Q05469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948413 0.79 MGLL (0.34)
SCHEMBL14948447 0.74 CYP2C19 (0.39) NPC1RAB9APAX8JAK2ALDH1A1
SCHEMBL14948362 0.73 CYP2C19 (0.33) CYP2C19
SCHEMBL22003157 0.73 LIPG (0.38) TP53
SCHEMBL13699887 0.71 ALDH1A1 (0.42) NPC1RAB9AALDH1A1TP53CYP2C19
SCHEMBL14948367 0.70 S1PR1 (0.33)
SCHEMBL14948342 0.70 CYP2C19 (0.36) NPC1RAB9AALDH1A1CYP2C19TACR1
SCHEMBL14981814 0.70 TAAR1 (0.44) ALDH1A1CYP2C19
SCHEMBL8669532 0.70 LIPG (0.43) ALDH1A1TP53CYP2C19
SCHEMBL14981535 0.70 TAAR1 (0.38) RAB9AALDH1A1TP53CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed