SCHEMBL14948445

SCHEMBL14948445

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc(CBr)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP14 P54578 1/20 0.36
POLB P06746 2/20 0.36
TP53 P04637 1/20 0.36
KMT2A Q03164 2/20 0.35
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
CACNB4 O00305 2/20 0.34
CACNA1A O00555 2/20 0.34
CACNA1G O43497 2/20 0.34
CACNG3 O60359 2/20 0.34
CACNA1F O60840 2/20 0.34
CACNA1H O95180 2/20 0.34
CACNB3 P54284 2/20 0.34
CACNA2D1 P54289 2/20 0.34
CACNG7 P62955 2/20 0.34
CACNA1B Q00975 2/20 0.34
CACNA1D Q01668 2/20 0.34
CACNB1 Q02641 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948448 0.93 POLB (0.38) USP14POLBTP53KMT2AMAPT
SCHEMBL4570430 0.86 POLB (0.38) USP14POLBTP53KMT2AMAPT
SCHEMBL15025823 0.85 POLB (0.44) USP14POLBKMT2AMAPTKDM4E
SCHEMBL10067482 0.84 TDP1 (0.41) USP14POLBTP53KMT2AMAPT
SCHEMBL9913062 0.83 POLB (0.46) USP14POLBTP53KMT2AMAPT
SCHEMBL10067484 0.81 MAPT (0.40) USP14POLBTP53MAPTLMNA
SCHEMBL18674305 0.80 ALDH1A1 (0.44) USP14POLBKMT2AMAPTLMNA
SCHEMBL38654780 0.80 ALDH1A1 (0.44) USP14POLBKMT2AMAPTLMNA
SCHEMBL14948328 0.80 POLB (0.38) USP14POLBTP53MAPTKDM4E
SCHEMBL14176722 0.80 TDP1 (0.39) USP14POLBTP53KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed