SCHEMBL14948448

SCHEMBL14948448

Cc1ccc(-n2c3ccc(C)cc3c3cc(CBr)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
TP53 P04637 2/20 0.37
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
CACNB4 O00305 1/20 0.35
CACNA1A O00555 1/20 0.35
CACNA1G O43497 1/20 0.35
CACNG3 O60359 1/20 0.35
CACNA1F O60840 1/20 0.35
CACNA1H O95180 1/20 0.35
CACNB3 P54284 1/20 0.35
CACNA2D1 P54289 1/20 0.35
CACNG7 P62955 1/20 0.35
CACNA1B Q00975 1/20 0.35
CACNA1D Q01668 1/20 0.35
CACNB1 Q02641 1/20 0.35
CACNG1 Q06432 1/20 0.35
CACNB2 Q08289 1/20 0.35
CACNA1S Q13698 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948445 0.93 USP14 (0.36) POLBTP53MAPTKDM4EGAA
SCHEMBL10067484 0.85 MAPT (0.40) POLBTP53MAPTKDM4EGAA
SCHEMBL9913062 0.84 POLB (0.46) POLBTP53MAPTKDM4EGAA
SCHEMBL14948328 0.84 POLB (0.38) POLBTP53MAPTKDM4EGAA
SCHEMBL4570430 0.83 POLB (0.38) POLBTP53MAPTKDM4EGAA
SCHEMBL15025823 0.82 POLB (0.44) POLBMAPTKDM4EGAAUSP14
SCHEMBL10067482 0.81 TDP1 (0.41) POLBTP53MAPTKDM4EGAA
SCHEMBL13231732 0.81 POLB (0.44) POLBTP53MAPTKDM4EGAA
SCHEMBL15784487 0.81 POLB (0.44) POLBTP53MAPTKDM4EGAA
SCHEMBL12544714 0.80 RORA (0.41) POLBTP53MAPTPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed