SCHEMBL14948650

SCHEMBL14948650

Cc1ccc(/C=C(\C#N)C(=O)O)nc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.45
KDM4E B2RXH2 3/20 0.45
CISD1 Q9NZ45 1/20 0.45
SLC16A3 O15427 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CYP3A4 P08684 1/20 0.45
HPGD P15428 1/20 0.45
SLC16A1 P53985 1/20 0.45
GPR35 Q9HC97 1/20 0.45
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16141474 0.77 AKR1C3 (0.44) KDM4EALDH1A1
SCHEMBL29899029 0.76 MAPT (0.55) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL26932950 0.76 RAB9A (0.40) KDM4EALDH1A1LMNAKMT2A
SCHEMBL26932629 0.76 RAB9A (0.40) KDM4EALDH1A1LMNAKMT2A
SCHEMBL995610 0.75 EGFR (0.71) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL995609 0.75 EGFR (0.71) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL1792662 0.75 EGFR (0.71) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL10906195 0.74 RAB9A (0.55) EGFRKDM4ECISD1SLC16A3ALDH1A1
SCHEMBL21726046 0.73 RAB9A (0.38) KDM4EALDH1A1LMNAKMT2A
SCHEMBL20240051 0.72 EGFR (0.57) EGFRKDM4ECISD1SLC16A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10562913-B2 Indolizine-based dyes for dye-sensitized solar cell UNIVERSITY OF MISSISSIPPI (US) 2020-02-18 US disclosed
EP-2776515-B1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-08-28 EP disclosed
US-20170226125-A1 INDOLIZINE-BASED DYES FOR DYE-SENSITIZED SOLAR CELL UNIVERSITY OF MISSISSIPPI 2017-08-10 US disclosed
US-20170226125-A1 INDOLIZINE-BASED DYES FOR DYE-SENSITIZED SOLAR CELL UNIVERSITY OF MISSISSIPPI 2017-08-10 US disclosed
US-9171676-B2 Organic colourant and uses thereof in photovoltaic cells COMMISSARIAT {dot over (A)} L'ĖNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (FR) 2015-10-27 US disclosed
US-20140290748-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2014-10-02 US disclosed
WO-2013068588-A1 ORGANIC COLOURANT AND USES THEREOF IN PHOTOVOLTAIC CELLS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2013-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226125-A1 INDOLIZINE-BASED DYES FOR DYE-SENSITIZED SOLAR CELL INMT, IDO1, IDO2 EGFR 3381/4885KDM4E 1805/4885CISD1 217/4885
US-10562913-B2 Indolizine-based dyes for dye-sensitized solar cell INMT, IDO1, IDO2 EGFR 3381/4885KDM4E 1805/4885CISD1 217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.