SCHEMBL21726046

SCHEMBL21726046

Cc1ccc(/C=C(\C=N)C(=O)O)nc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.38
MAPT P10636 1/20 0.38
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32
RXRA P19793 1/20 0.32
KDM4E B2RXH2 4/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADRA2A P08913 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 2/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16141474 0.78 AKR1C3 (0.44) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL26932950 0.77 RAB9A (0.40) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL26932629 0.77 RAB9A (0.40) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL14948653 0.73 RAB9A (0.37) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL14948650 0.73 EGFR (0.45) KDM4EALDH1A1LMNAKMT2A
SCHEMBL14042504 0.71 CCR1 (0.44) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL1124264 0.70 KDM4E (0.46) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL1124263 0.70 KDM4E (0.46) RAB9AMAPTCCR1CCR5CCR8
SCHEMBL22319799 0.69 ALDH1A1 (0.47) RAB9AMAPTRARARARBRARG
SCHEMBL5666359 0.68 RAB9A (0.44) RAB9AMAPTCCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10562913-B2 Indolizine-based dyes for dye-sensitized solar cell UNIVERSITY OF MISSISSIPPI (US) 2020-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562913-B2 Indolizine-based dyes for dye-sensitized solar cell INMT, IDO1, IDO2 RAB9A 1212/4885MAPT 2311/4885CCR1 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.