Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813029 | 0.83 | KDM4E (0.50) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL31360784 | 0.83 | CA2 (0.39) | SMN1; SMN2MME | |
| SCHEMBL29599134 | 0.83 | KDM4E (0.50) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL27791865 | 0.79 | KDM4E (0.38) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL28113681 | 0.79 | FOLH1 (0.52) | FOLH1NAALAD2 | |
| SCHEMBL23641598 | 0.79 | — | — | |
| SCHEMBL27597011 | 0.77 | KMT2A (0.42) | ALOX15BLMFOLH1NAALAD2KMT2A | |
| SCHEMBL27597009 | 0.77 | KMT2A (0.42) | ALOX15BLMFOLH1NAALAD2KMT2A | |
| SCHEMBL1287220 | 0.74 | — | — | |
| SCHEMBL13248610 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975283-B2 | Pharmacologically active compounds containing sulfur | JON PTY LIMITED (AU) | 2015-03-10 | — | — | US | disclosed |
| US-20130123504-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | JON PTY LIMITED (AU) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123504-A1 | PHARMACOLOGICALLY ACTIVE COMPOUNDS CONTAINING SULFUR | SCLY, STS, SQOR | TGFBR1 1722/4885KDM4E 4559/4885MAPT 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.