SCHEMBL14949075

SCHEMBL14949075

CNC(Cc1cccnc1)C(=O)C(C)C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.51
FDPS P14324 1/20 0.48
PKM P14618 1/20 0.46
KMT2A Q03164 1/20 0.46
NAPRT Q6XQN6 1/20 0.45
LMNA P02545 3/20 0.45
FPR1 P21462 1/20 0.44
HTT P42858 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RECQL P46063 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ECE1 P42892 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511421 0.87 TBXAS1 (0.47) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL15185855 0.86 KMT2A (0.47) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL10140580 0.86 TBXAS1 (0.49) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL31370303 0.85 TBXAS1 (0.57) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL14898388 0.85 TBXAS1 (0.50) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL29794532 0.85 TBXAS1 (0.57) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL30937414 0.85 TBXAS1 (0.57) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL6220905 0.85 TBXAS1 (0.57) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL12220088 0.85 TBXAS1 (0.50) TBXAS1FDPSPKMKMT2ANAPRT
SCHEMBL14640282 0.85 TBXAS1 (0.57) TBXAS1FDPSPKMKMT2ANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130123170-A1 Growth Hormone Releasing Peptides IPSEN PHARMA, S.A.S. (FR) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123170-A1 Growth Hormone Releasing Peptides GHRHR, THRB, PRLHR TBXAS1 3764/4885FDPS 2461/4885PKM 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.